Exposome-omics-Wide Association Study (ExWAS)

This web application can be used to query and download findings from the Exposome-omics-Wide Association Study (ExWAS) conducted in the Human Early Life Exposome (HELIX) project, including 1,301 school-age children from 6 European cohorts in the UK, France, Spain, Lithuania, Norway and Greece (https://www.projecthelix.eu").
This is a unique and comprehensive resource of molecular signatures related to common environmental exposures during vulnerable early life stages. Maitre, L., Bustamante, M., Hernandez-Ferrer, C. et al. Mutil-omics signatures of the human early life exposome. Nat Commun 13, 7024 (2022).https://doi.org/10.1038/s41467-022-34422-2

Scroll down to download other HELIX results.

OTHER HELIX RESULTS

Together with the ExWAS catalogue, we provide links to summarized results of other omics analyses in HELIX. To download summarized results, click on the links below.

Study	Codebook	Result tables	Filesize
In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children (PMID: 32811491)	HELIX_smok_omics_READMEfile.xlsx	HELIX_smok_omics_WebCat.tar.gz	68M
Urinary metabolite quantitative trait loci in children and their interaction with dietary factors (PMID: 33283231)	HELIX_urine_metabQTL_READMEfile.xlsx	HELIX_urine_metabQTL_WebCat.tar.gz	511M
Identification of blood autosomal cis-expression quantitative trait methylation (cis-eQTMs) in children	HELIX_Blood_eQTM_READMEfile.xlsx	eQTM_autosome_adj.cells_SIG.txt.gz eQTM_autosome_adj.cells.txt.gz eQTM_autosome_unadj.cells_SIG.txt.gz eQTM_autosome_unadj.cells.txt.gz eQTM_SNPs_autosome_unadj.cells.txt.gz	2M 541M 3M 542M 43M
Green space exposure and blood DNA methylation at birth and in childhood - a multi-cohort study	EWAS_GS_blood_READMEfile.xlsx	EWAS_GS_blood_summarized_results.zip	199M
Blood miRNA quantitative trait loci (blood miQTL)	Coming soon	Coming soon	Not available